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Introduction

The M. Sc. Microbiology programme was started at TribhuvanUniversity in 1990 for the first time in Nepal at the Central Department of Microbiology, TribhuvanUniversity, Kirtipur. The course structure of the programme was changed in 1999 and revised in 2008 and 2009. However, the course was based on the annual examination system.The course structure of the programme was changed into semester system in 2013.Therefore, this is a revised semester system credit based course curriculum to make it more competitive and research oriented.

 The present curriculum is designed to upgrade M.Sc. Microbiology degree of Institute of Science and Technology, TribhuvanUniversity to international level in accordance to current advances in Microbiology. The new curriculum emphasizes on research based teaching learning practice. The new M.Sc. Microbiology degree programme will be semester system credit based as per international trend. The present curriculum aims to produce qualified microbiologists, molecular biologists, researchers and scientists as per national and international demand. The Master's degree holders will be able to use skills of modern molecular biology techniques in basic science research or in applied research areas of Microbiology. The graduates will be able to work as a qualified scientist for investigating the potential uses of microorganisms to produce antibiotics, antibodies, steroids, vaccines, hormones and other products of microbial origin. The Master's degree holders will be able to work as a microbiologist and research scientist in the laboratories for monitoring, identifying and helping to control infectious diseases.They will also be able to work as qualified researchers and scientists in the institutions related to food production, crop protection and soil fertility. The Master's degree holders will be eligible to be the lecturers of Microbiology programme offered by Institute of Science and Technology and other institutions of Tribhuvan University or other universities for teaching, mentoring and supervising bachelors and masters level Microbiology students.

 Course Structure

 The entire course is divided into four semesters within two academic years. The first semester course covers the disciplines of General Microbiology, Immunology, Microbial Genetics, Microbial Biochemistry and practical on these courses. The second semester offers track selection among four different disciplines of Microbiology for specialization. The four disciplines from second semester include Medical Microbiology, Public Health Microbiology, Food Microbiology and Agricultural Microbiology with their practical courses. The fourth semester is completely research oriented that includes special topics in Microbiology, Epidemiology, Research Methods and Biostatistics, and Dissertation. In the second semester students are required to choose one of the four different disciplines offered and continue with it through the Third and Fourth semesters. Students are not allowed to change the discipline once they have chosen it. The selection of discipline of Microbiology may depend upon the facilities available at the department. To gain exposure, students are encouraged to go for excursion after the second semester.

  Eligibility and Admission Procedures

 Candidates having a Bachelor’s Degree in Microbiology from Tribhuvan University or equivalent degree recognized by Tribhuvan University are eligible to apply for the M. Sc. Microbiology programme. Each applicant should appear and pass entrance examination conducted by the Central Department of Microbiology. The enrollment will be based on merit. The candidates failed to get minimum qualifying marks/pass marks in the entrance examination will not be enrolled in the program.

 Hours of Instruction

 Working days: 90 days in a semester

  1. Class hours:
  • Theory: One credit is equivalent to 15 teaching hours in a semester. One theory paper of 1 credit will have 1 hour of lecture per week
  • Practical: One credit is equal to 60 practical hours in a semester. One practical paper of 1.5 or 1 credit will have 4 hours of practical per week

Total Credits: 70 credits within four semesters.

 Attendance

 Student should be regular in their classes. Students failing to maintain 80 percent presence are not allowed to appear in the semester-end examinations and regarded as “not qualified”. However, in case of serious illness the students with 70 percent attendance will be given chance to appear in the semester-end exam. In this case students have to submit an authorized medical certificate.

 Normal and Maximum Duration of Study

 The normal duration and the maximum duration for the completion of the requirements for the program is as follows:

             Normal duration          24 months (4 academic semesters)

            Maximum duration     60 months (10 academic semesters)

 Students failing to complete the requirements in 60 months have to re-enroll.

 Teaching Methodology

 The general teaching methodology of the program includes interactive lectures, students’ presentations, case studies and projects.

 Language of Instruction: English

 Examination

 Students must pass the internal assessment in order to appear for the final examination. There will be two internal assessments which will count as 40% internal evaluation. The pass marks for theory is 50% and practical subjects are 50%. Institute of Science and Technology, Tribhuvan University will conduct semester examination. The final semester examination of 1 credit theory subject will have 1 hour of duration (3C≈3 hrs) and internal assessment will have one hour of duration for all subjects.

 Evaluation/ Examination

The evaluation is based on the internal evaluation and final semester examination. The internal evaluation which is 40% of total evaluation is done by the department based on different criteria of evaluation listed below;

Internal evaluation (40%):

 1. Attendance: 5 marks

2. Seminar/class test/home assignment: 5 marks

3. Project work/ case study: 5 marks

4. Mid term  exam: 10 marks

5. Final term evaluation: 15 marks

The remaining 60% of the evaluation is done from semester examination taken at the end of the semester. The semester examination will be conducted by the office of the Dean of Science and Technology. Students are required to obtain 50 percent to pass internal exam (evaluation) as well as semester end examination.

 Make-up/retake examination

Students failing in not more than two subjects in first, second and third semester shall appear in make-up exams in following cycle of exams. Students failing in two subjects in the fourth semester shall be given opportunity to appear in make-up exam within one month after the final result.

 Grading

 Total marks obtained in internal and semester-end exams shall be graded on absolute bases.

 The performance of a student shall be made on four point scale ranging from 0 to 4 grades. A student must secure a minimum Grade Point Average (GPA) of 2.7 or Grade B minus (B-) in each course.

 Absolute grading scale

 

Grade

CGPA

Percentage Equivalent

Performance Remarks

A

4.0

90 and above

Distinction

A-

3.7

80-89.9

Very good

B+

3.3

70-79.9

First Division

B

3.0

60-69.9

Second Division

B-

2.7

50-59.9

Pass in individual subject

F

0

Below 50

Fail

 The students shall receive their semester grades and academic transcript grades only in letter grades and GPA scores. Students securing only 2.7 in grade point are considered as “pass in individual subject”.

In order to pass the semester examination the student must secure a minimum of Grade ‘B’ or Cumulative Grade Point Average (CGPA) of 3.0. A student who secures CGPA less than 3 may request for the opportunity to  improve the grade in two subjects. The office of the dean will provide one time opportunity to appear in semester exam. The exam of the courses to improve grade shall be held as per course cycle.

Courses

 Semester I

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 501

General Microbiology (Microbial Systematics, Structure and Physiology)

T

3

75 (45+30)

MB 502

Immunology and Immunochemical Techniques

T

3

75 (45+30)

MB 503

Microbial Genetics and Molecular Biology

T

3

75 (45+30)

MB 504

Biochemistry and Instrumentation

T

3

75 (45+30)

MB 505

Practical on (MB 501 + MB 502)

P

3

75

MB 506

Practical on (MB 503 + MB 504)

P

3

75

Total

18

450

 

Discipline I: Public Health Microbiology

 Semester II

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 551

Human Anatomy and Physiology

T

3

75 (45+30)

MB 552

Applied Environmental Microbiology

T

3

75 (45+30)

MB 553

Fundamentals of Epidemiology

T

3

75 (45+30)

MB 554

Microbial Systematics

T

3

75 (45+30)

MB 555

Practical on (MB 551 + MB 552)

P

3

75

MB 556

Practical on (MB 553 + MB 554)

P

3

75

Total

18

450

 Semester III

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 601

Microbial Biotechnology and Pharmaceutical Microbiology

T

3

75 (45+30)

MB 602

Public Health Microbiology

T

3

75 (45+30)

MB 603

Emerging Infectious Diseases

T

3

75 (45+30)

MB 604

Public Health Laboratory

T

3

75 (45+30)

MB 605

Practical on (MB 601 + MB 602)

P

3

75

MB 606

Practical on (MB 603 + MB 604)

P

3

75

Total

18

450

 Semester IV

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 651

 Research Methods and Biostatistics

T

3

75(45+30)

MB 652

Journal club/Seminar

T

1

25

MB 653

Hospital/Field Based Internship

P

8

200

MB 654

Dissertation

P

4

100

Total

16

400

 Discipline II: Medical Microbiology

 Semester II

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

MB 551

Human Anatomy and Physiology

T

3

75 (45+30)

MB 557

Systematic  and Diagnostic Bacteriology  -1

T

3

75 (45+30)

MB 558

Systematic  and Diagnostic Virology-1

T

3

75 (45+30)

MB 559

Systematic  and Diagnostic Parasitology-1

T

2

50 (30+20)

MB 560

Systematic  and Diagnostic Mycology -1

T

1

25 (15+10)

MB 561

Practical on (MB 551 + MB 557)

P

3

75

MB 562

Practical on (MB 558 + MB 559 + MB 560)

P

3

75

Total

18

450

 Semester III

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

MB 601

Microbial Biotechnology and Pharmaceutical Microbiology

T

3

75 (45+30)

MB 607

Systematic and Diagnostic Bacteriology-2

T

3

75 (45+30)

MB 608

Systematic and Diagnostic Virology-2

T

3

75 (45+30)

MB 609

Systematic and Diagnostic Parasitology -2

T

2

50 (30+20)

MB 610

Systematic and Diagnostic Mycology  -2

T

1

25 (15+10)

MB 611

Practical on (MB 601 + MB 607)

P

3

75

MB 612

Practical on (MB 608 + MB 609  + MB 610)

P

3

75

Total

18

450

 Semester IV

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory course

MB 651

 Research Methods and Biostatistics

T

3

75(45+30)

MB 655

Journal club/Seminar

T

1

25

MB 656

Hospital Based Internship

P

8

200

MB 657

Dissertation

P

4

100

Total

16

400

Discipline III: Food and Industrial Microbiology

 Semester II

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 563

Microbial Biotechnology and Industrial Microbiology

T

3

75 (45+30)

MB 564

Pharmaceutical Microbiology

T

3

75 (45+30)

MB 565

General Food Microbiology

T

3

75 (45+30)

MB 566

Foodborne Pathogens and Toxicology 

T

3

75 (45+30)

MB 567

Practical on (MB 563 + MB 564)

P

3

75

MB 568

Practical on (MB 565 + MB 566)

P

3

75

Total

18

450

 Semester III

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 613

Food Fermentation Technology

T

3

75 (45+30)

MB 614

Food Biotechnology

T

3

75 (45+30)

MB 615

Food Preservation and Processing

T

3

75 (45+30)

MB 616

Total Quality Management and Quality Assurance

T

3

75 (45+30)

MB 617

Practical on (MB 613 + MB 614)

P

3

75

MB 618

Practical on (MB 615 + MB 616)

P

3

75

Total

18

450

 Semester IV

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 651

Research Methods and Biostatistics

T

3

75 (45+30)

MB 658

Journal club/Seminar

T

1

25

MB 659

Industry based Internship

P

8

200

MB 660

Dissertation

P

4

100

Total

16

400

 Discipline IV: Agriculture Microbiology

 Semester II

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 563

Microbial Biotechnology/Industrial Microbiology

T

3

75 (45+30)

MB 569

Soil Microbiology

T

3

75 (45+30)

MB 570

Microbial Metabolism in Soil

T

3

75 (45+30)

MB 571

Soil Fertilizers

T

3

75 (45+30)

MB 572

Practical on (MB 563 + MB 569)

P

3

75

MB 573

Practical on (MB 570 + MB 571)

P

3

75

Total

18

450

 Semester III

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 619

Biological Control

T

3

75 (45+30)

MB 620

Insect Microbial Pathology

T

3

75 (45+30)

MB 621

Agricultural Pest Management

T

3

75 (45+30)

MB 622

Applied Soil Microbiology

T

3

75 (45+30)

MB 623

Practical on (MB 619 + MB 620)

P

3

75

MB 624

Practical on (MB 621 + MB 622)

P

3

75

Total

18

450

 Semester IV

 

Course code

Course title

Nature of course

Credits

Evaluation (40% internal assessment)

Compulsory courses

MB 651

 Research Methods and Biostatistics

T

3

75 (45+30)

MB 661

Journal club/Seminar

T

1

25

MB 662

Agriculture Based Internship

P

8

200

MB 663

Dissertation

P

4

100

Total

16

400

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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